My goal was to get 1080p, at a reasonable file size and processing time. I don't have a whole lot of time to let my computer render since I don't have a second machine, and I'm recording up to 30 min videos sometimes, which can generate large files. This is just a hobby for me, so I've found settings that work well for what I want!
On my channel there are videos of different quality because I used them for testing the "render on the fly" option of bandicam (which is amazing by the way) but my microphone input needs to be cleaned in Premiere Pro, so I use the post render settings above, which also takes less system resources when I'm playing and recording (to the point where I don't even notice much frame drop at all.) I will only be post-rendering in the future as it offers the best option for me, and I'm very glad I bought this software!
Here's my channel https://www.youtube.com/user/janzer247 I mainly record Borderlands 2. I hope this helps someone, as when I first started using Bandicam I was amazed at the awesomeness of the product, but there were other factors I needed help with such as Premiere Pro!